Can the kidney function as a lung? Systemic oxygenation and renal preservation during retrograde perfusion of the ischaemic kidney in rabbits

MR Humphreys, MH Ereth, TJ Sebo… - BJU …, 2006 - Wiley Online Library
OBJECTIVE To investigate renal preservation by a novel method of perfusion using an
oxygenated perfluorocarbon (PFC) emulsion via retrograde access to the kidney, as
preserving renal function during urological surgery has been elusive, and the recognized
technique of nephron‐sparing surgery has increased its application and practice in modern
urology. MATERIALS AND METHODS After institutional review and approval, 30 New
Zealand White rabbits were studied. In a solitary kidney model, each rabbit had the ureter …
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